Biomaterials Consulting & Dhizaini & Kuvandudza

Biomaterials zvinhu zvechisikigo kana kugadzirwa nevanhu, izvo zvinosanganisira yakazara kana chikamu chechimiro chekugara kana biomedical mudziyo unoshanda, unowedzera, kana kutsiva basa rechisikigo. Biomaterials inoshandiswa mune zvekurapa kunyorera mazino, kuvhiyiwa, uye kuendesa zvinodhaka (chivakwa chine zvigadzirwa zvemishonga zvakaiswa zvinogona kuiswa mumuviri, izvo zvinobvumidza kuburitswa kwenguva refu kwemushonga kwenguva yakareba). Biomaterials inogona kunge iine benign basa, sekushandiswa kwevharuvhu yemoyo, kana inogona kunge iri bioactive ine inopindirana inoshanda senge hydroxy-apatite yakavharwa hudyu implants. Biomaterials inogona kunge yakagadzirwa nevanhu zvinhu zvakavakwa nesimbi, ceramics, kana kuve autografts, allografts kana xenografts inoshandiswa semidziyo yekuisa.

Biomaterials inoshandiswa zvakanyanya mu:

• Bone simenti

• Bone plates

• Joint replacements

• Artificial ligaments & tendons

• Mitsipa yeropa prostheses

• Mavharuvhu emwoyo

• Zvigadzirwa zvekugadzirisa ganda

• Kuiswa kwemazino

• Cochlear replacements

• Contact lenzi

• Kuiswa muzamu

• Zvimwe zvinoiswa mumuviri

Biomaterials kuenderana (biocompatibility) nemuviri inofanirwa kugadziriswa uye kuvimbiswa chigadzirwa chisati chaiswa pamusika uye kushandiswa munzvimbo yekiriniki. Nekuda kweizvi, biomaterials inowanzoiswa kune zvakafanana zvinodiwa zveavo vanoitwa nemishonga mitsva yemishonga. Biocompatibility ine hukama nemaitiro ebiomaterials munzvimbo dzakasiyana siyana pasi peakasiyana makemikari uye emuviri mamiriro. Biocompatibility inogona kureva kune chaiyo zvivakwa zvechinhu pasina kutsanangura kuti chinhu chacho chinoshandiswa kupi kana kuti sei. Semuyenzaniso, chinhu chinogona kuunza kushoma kana kusashaya mhinduro yekudzivirira mumuviri mune yakapihwa chisikwa, uye inogona kana kusakwanisa kubatanidzwa neimwe sero rudzi kana tishu). Zvishandiso zvemazuva ano zvekurapa uye ma prostheses zvinowanzogadzirwa kubva kune akati wandei akasiyana zvinhu, saka hazvigoneke nguva dzose kutaura nezve biocompatibility yechinhu chakati.

Uyezve, chinhu hachifanire kuve chine muchetura kunze kwekunge chakanyatso kugadzirwa kuti ive senge smart dhizaini masisitimu anonangana nekenza maseru kuti avaparadze. Kunzwisisa kweanatomy uye physiology yenzvimbo yekuita kwakakosha kuti biomaterial ishande. Chimwe chinhu chinowedzera kutsamira pane chaiyo anatomical nzvimbo dzekuisa. Saka zvakakosha, panguva yekugadzira biomaterials, kuve nechokwadi chekuti chishandiso chinokwana zvakaenzana uye chine mhedzisiro inobatsira nenzvimbo yeanatomical yekuita.

MABASA EDU

Isu tinopa biomaterials dhizaini, kusimudzira, ongororo uye kuyedza masevhisi anotsigira kusimudzira uye kubvumidzwa kwemusika kwemidziyo yekurapa uye musanganiswa wemidziyo yezvinodhaka, kubvunza, chapupu chehunyanzvi uye masevhisi ematare.

KUGADZIRA NEKUDZIDZWA KWEZVINOGONA

Yedu biomaterials dhizaini uye ekusimudzira mainjiniya uye masayendisiti ane hunyanzvi mukugadzira nekugadzira biomaterials kune makuru evagadziri eIVD ane mhedzisiro yakasimbiswa mumakiti ekuongorora. Biological tishu dzakarongeka mukati mezvikero zvakawanda, dzinoita akawanda maumbirwo uye emuviri mabasa. Biomaterials inoshandiswa kutsiva iyo biological tishu uye inofanirwa kugadzirwa nenzira imwecheteyo. Nyanzvi dzedu dzezvidzidzo dzine ruzivo uye ruzivo mune zvakawanda zvesainzi zvezvinhu izvi zvakaoma uye mashandisirwo anosanganisira biology, physiology, makanika, simulation yenhamba, chemistry yemuviri ... nezvimwe. Hukama hwavo hwepedyo uye ruzivo nekutsvagisa kwekiriniki uye kuwana nyore kune akawanda maitiro uye maitiro ekuona zvinhu zvedu zvakakosha.

Imwe nzvimbo huru yekugadzira, "Biointerfaces" yakakosha pakutonga kwesero mhinduro kune biomaterials. Biochemical uye physico-makemikari zvimiro zvebiointerfaces zvinogadzirisa sero kunamatira kune biomaterials uye kutorwa kwenanoparticles. Mabhurashi epolymer, cheni dzepolymer dzakasungirirwa kune imwe mugumo chete kune yepasi substrate mabhanhire ekudzora akadaro biointerface. Aya machira anobvumira kuenzanisa iyo physico-kemikari zvimiro zvebiointerfaces kuburikidza nekutonga kwehukobvu hwadzo, kusimba kwecheni uye kemikari yezvikamu zvadzo zvekudzokorora uye inogona kuiswa kune simbi, ceramics uye mapolymer. Mune mamwe mazwi, ivo vanobvumira kugadziridzwa kweiyo bioactive zvimiro zveakasiyana ezvigadzirwa, zvisinei nehuwandu hwazvo uye makemikari epamusoro. Mainjiniya edu ebiomaterial akadzidza kunamatira kweprotein uye kupindirana kune mabhurashi epolymer, vakaongorora maitiro ebiofunctional emabiomolecules akasanganiswa nemabhurashi epolymer. Zvidzidzo zvavo zvakadzika zvakabatsira mukugadzira machira ekuisa, mu vitro cell tsika masisitimu uye nekugadzirwa kwemajini ekutumira mavector.

Inodzorwa geometry chinhu chakasikwa chematishu uye nhengo mu vivo. Iyo geometrical chimiro chemasero uye matishu paakawanda kureba zviyero zvakakosha kune yavo basa uye basa, uye chiratidzo chezvirwere zvakaita segomarara zvakare. In vitro, uko masero ari tsika pamidziyo yepurasitiki yekuyedza, kutonga uku kwejometri kunowanzorasika. Kuvaka patsva nekudzora zvimwe zve geometrical maficha ebiological masisitimu mu vitro kwakakosha mukuvandudzwa kwetishu engineering scaffolds uye dhizaini yemasero akavakirwa maassays. Ichabvumira kutonga kuri nani kwesero phenotype, yakakwirira dhigirii chimiro uye basa, izvo zvakakosha pakugadzirisa matishu. Izvi zvinobvumira kunyatsoita kuwanda kwesero uye organoid maitiro mu vitro uye kutsunga kwekuita kwemishonga uye marapirwo. Yedu biomaterials mainjiniya akagadzira mashandisirwo ezvishandiso zvepatani pazvikero zvehurefu hwakasiyana. Aya maitiro ekuita maitiro anofanirwa kunyatsoenderana nekemikari yebiomaterials pakavakirwa mapuratifomu aya, pamwe chete neakakodzera sero tsika mamiriro.

Kune zvimwe zvakawanda zvekugadzira nekusimudzira nyaya dzakashanda nemainjiniya edu ebiomaterials mumabasa avo ese. Kana iwe uchida ruzivo rwakakwana nezve chimwe chigadzirwa ndapota taura nesu.

BIOMATERIALS TESTING SERVICES

Kugadzira, kugadzira uye kugadzira zvakachengeteka uye zvinobudirira zvigadzirwa zvebiomaterial, uchisangana nezvinodiwa zvepamutemo zvemvumo yekushambadzira, kuongororwa kwakasimba murabhoritari kunodiwa kuti unzwisise zvinhu zvine chekuita nekuchengetedzwa kwechigadzirwa, senge maitiro ezvigadzirwa zvebiomaterial kuburitsa zvinhu zvinoburitswa, kana kuita. maitiro, akadai sema mechanical properties. Tinokwanisa kuwana huwandu hwakasiyana-siyana hwekugona kuongorora kuitira kuti tinzwisise kuzivikanwa, kuchena, uye biosafety yehuwandu huri kukura hwezvinhu zvipenyu zvinoshandiswa mumishonga yemishonga kuburikidza nemuviri, kemikari. , mechaniki, uye microbiological yekuongorora nzira. Sechikamu chebasa redu isu tinobatsira vagadziri kuongorora kuchengetedzwa kwemidziyo yapera nekutsigira toxicological consulting. Isu tinopa masevhisi ekuongorora kutsigira kugadzirwa kwechigadzirwa uye kutonga kwemhando yezvigadzirwa uye zvigadzirwa zvakapedzwa. Tine ruzivo nemhando dzakawanda dzebiomaterials sezvinwiwa, gels, mapolymers, simbi, ceramics, hydroxyapatite, composites, pamwe chete nebiologically sourced zvinhu senge collagen, chitosan, peptide matrices, uye alginates. Mimwe miedzo mikuru yatinogona kuita ndeiyi:

• Kemikari hunhu uye elemental ongororo yebiomaterials kuti uwane kunzwisiswa kwakazara kwechigadzirwa chekutumira kwekutonga uye yekuzivikanwa kana kuwanda kwezvakasvibiswa kana zvinosvibisa zvigadzirwa. Isu tinokwanisa kuwana maLab akashongedzerwa nehupamhi hwehunyanzvi hwekuona kuumbwa kwemakemikari, senge infrared spectroscopy (FTIR, ATR-FTIR) ongororo, nuclear magnetic resonance (NMR), size exclusion chromatography (SEC) uye inductively-coupled plasma. spectroscopy (ICP) kuona uye kuverengera kuumbwa uye kutsvaga zvinhu. Ruzivo rwekutanga nezve iyo biomaterial nzvimbo inowanikwa neSEM / EDX, uye yezvakawanda zvinhu neICP. Aya matekiniki anogona zvakare kuratidza kuvepo kweanogona kuita chepfu simbi senge lead, mercury uye arsenic mukati uye pane biomaterials.

• Kusachena hunhu uchishandisa murabhoritari-chiyero chekuzviparadzanisa nevamwe uye huwandu hwechromatography kana misa spectrometry nzira dzakadai seMALDI-MS, LC-MSMS, HPLC, SDS-PEJI, IR, NMR uye fluorescence ... nezvimwe.

• Biomaterial polymer ongororo yekutarisa iyo yakawanda polymer zvinhu pamwe nekuona iyo yekuwedzera mhando senge plasticizers, colorants, anti-oxidants uye mafirita, tsvina yakaita seisina kubatwa monomers uye oligomers.

• Kutemerwa kwemhando dzebiological dzekufarira dzakadai seDNA, Glycoaminoglycans, yakazara mapuroteni emukati ... nezvimwe.

• Ongororo yezvinobatika zvakabatanidzwa mune biomaterials. Isu tinoitisa zvidzidzo zvekuongorora kutsanangura kuburitswa kunodzorwa kweaya mamorekuru anoshanda senge mishonga inorwisa utachiona, antimicrobials, synthetic polymers uye inorganic marudzi kubva kune biomaterials.

• Isu tinoitisa zvidzidzo zvekuzivikanwa uye kuwanda kwezvinhu zvinobviswa uye zvinobvisika izvo zvinobva kune biomaterials.

• GCP uye GLP bioanalytical masevhisi anotsigira ese matanho ekuvandudza zvinodhaka uye asiri-GLP nekukurumidza kuwanikwa chikamu bioanalysis.

• Elemental ongororo uye kuteedzera masimbi kuyedza kutsigira kusimudzira kwemishonga uye GMP kugadzira

• GMP kugadzikana zvidzidzo uye ICH kuchengetedza

• Kuyedzwa kwemuviri uye morphological uye hunhu hwezvinhu zvipenyu zvakaita sehukuru hwepore, pore geometry uye pore saizi kugovera, kubatana, uye porosity. Matekinoroji akadai semwenje microscope, scanning electron microscopy (SEM), nzvimbo dzekutemerwa neBET dzinoshandiswa kuratidza zvinhu zvakadaro. X-Ray diffraction (XRD) maitiro anoshandiswa kudzidza dhigirii rekristallinity uye chikamu mhando mumidziyo. 

• Mechanical uye kupisa kwekuyedza uye hunhu hwebiomaterials zvinosanganisira tensile bvunzo, kushushikana-kunetseka uye kutadza flex kuneta kuyedzwa nekufamba kwenguva, hunhu hwe viscoelastic (dynamic mechanical) zvivakwa uye zvidzidzo zvekutarisa kuora kwezvivakwa panguva yekuparara.

• Medical mudziyo kutadza kuongororwa, kutsunga kwechikonzero chemudzi

CONULTING SERVICES

Isu tinogona kukubatsira kusangana nehutano, kwezvakatipoteredza uye zvekutonga zvinodiwa, kuvaka chengetedzo uye mhando mudhizaini maitiro uye chigadzirwa, uye kugadzirisa maitiro ekugadzira. Edu mabiomaterials mainjiniya ane hunyanzvi mukugadzira, kuyedza, zviyero, manejimendi ekutengesa, tekinoroji, kuteedzera, toxicology, manejimendi eprojekiti, kuvandudza mashandiro, chengetedzo uye vimbiso yemhando. Mainjiniya edu ekubvunza anogona kumisa nyaya dzisati dzave matambudziko, kubatsira kubata uye kuongorora njodzi nenjodzi, kupa mhinduro nyowani kumatambudziko akaomarara, kupa mazano ekugadzira, kuvandudza maitiro uye kugadzira nzira dzakanakisa dzekugadzirisa kushanda nesimba.

NYANZVI WITNESS AND LITIGATION SERVICES

AGS-Engineering biomaterials mainjiniya nemasaenzi vane ruzivo mukupa bvunzo dzepatent uye zvigadzirwa zvemutemo zviito zvemutemo. Vakanyora Rule 26 nyanzvi mishumo, vakabatsira mukuvaka kwekuda, vakapupura mukuisa uye kutongwa mumatare anosanganisira mapolymers, zvinhu, uye michina yekurapa ine chekuita nezvese patent uye kesi yemhosva yechigadzirwa.

Kuti ubatsirwe nedhizaini, kusimudzira uye kuyedzwa kwebiomaterials, taura nesu nhasi uye edu biomaterials mainjiniya achafara kukubatsira.

Kana iwe uchinyanya kufarira yedu yakajairika kugadzira kugona panzvimbo yeinjiniya kugona, tinokukurudzira kuti ushanyire yedu tsika yekugadzira saitihttp://www.agstech.net

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Yedu FDA uye CE zvigadzirwa zvekurapa zvakatenderwa zvinogona kuwanikwa pa zvigadzirwa zvedu zvekurapa, zvinoshandiswa uye saiti yemidziyo.http://www.agsmedical.com